Great piece HERE on how careful high quality observation (not experiment) by Japanese physicists at the Super Kamiokande over a 20 year period have not seen proton decay - and not supported some of the most cherished Grand Unified Theories of theoretical physicists.
Q: How could it be that nature isn't as mathematically beautiful as thousands of mathematical physicists willed that it must be so?
A: The Mind Projection Fallacy strikes again.
Another story to file under the heading of Thomas Henry Huxley's assertion:
The great tragedy of Science - the slaying of a beautiful hypothesis by an ugly fact.